Tibetan medicine system is one of the oldest medicine forms in the world. It utilizes up to two thousand types of plants, forty animal species, and fifty minerals. Though it originated in the pre – Buddhist era, it developed progressively after the coming  of Buddhism. With the coming of Buddhism, the medical knowledge became an integral part of religious doctrines and monastic discipline. One of the renowned eighth century Buddhist physician Yutok Yonten Gonpo, created the important Four Medical Tantras assimilating material from the medical traditions of Persia, India and China. His descendant further strengthened the tradition by adding eighteen medical works.